Premalignant lesion diagnosis in Dental Clinic
PREMALIGNANT LESIONS IN ORAL CAVITY
Classification schemes for lesions of the oral cavity typically have used the clinical appearance of lesions to determine which are premalignant. (1) Leukoplakia and erythroplakia are two clinical lesions widely considered to be premalignant. However, using clinical features to classify lesions is difficult because they vary in appearance and are likely to be interpreted subjectively by the clinician. A histopathologic diagnosis is generally more indicative of premalignant change than clinically apparent alterations.
A State of the Science
Clinical Lesions Associated with Premalignancy
Leukoplakia
The term leukoplakia is sometimes used inappropriately to indicate a premalignant condition. In fact, the term describes a white plaque that does not rub off and cannot be clinically identified as another entity. Most cases of leukoplakia are a hyperkeratotic response to an irritant and are asymptomatic,
but about 20% of leukoplakic lesions show evidence of dysplasia or carcinoma at first clinical recognition.(1) However, some anatomic sites (floor of mouth and ventral tongue) have rates of dysplasia or carcinoma as high as 45%. There is no reliable correlation between clinical appearance and the histopathologic presence of dysplastic changes except that the possibility of epithelial
dysplasia increases in leukoplakic lesions with interspersed red areas. In one large study, (2) lesions with an erythroplakic component had a 23.4% malignant transformation rate, compared with a 6.5% rate for lesions that were homogeneous. The term erythroleukoplakia has been used to describe
leukoplakias with a red component.
Erythroplakia
An erythroplakia is a red lesion that cannot be classified as another entity. Far less common than leukoplakia, erythroplakia has a much greater probability (91%) of showing signs of dysplasia or malignancy at the time of diagnosis.(3) Such lesions have a flat, macular, velvety appearance and may be speckled with white spots representing foci of keratosis.
Lichen planus
The premalignant or malignant potential of lichen planus is in dispute. Some believe that the occasional epithelial dysplasia or carcinoma found in patients with this relatively common lesion may be either coincidental or evidence that the initial diagnosis of lichen planus was erroneous.(4) It is frequently difficult to differentiate lichen planus from epithelial dysplasia; one study found that 24% of oral lichen planus cases had 5 of the 12 World Health Organization (WHO) diagnostic criteria for epithelial dysplasia, and only 6% had no histologic features suggestive of that disorder. (5) However, Oral Cancer Background Papers as many reports on lichen planus patients followed over time indicate a higher than expected rate of malignant transformation,(6) it is prudent practice to biopsy the lesion at the initial visit to confirm the diagnosis and to monitor it thereafter for clinical changes suggesting a premalignant or malignant change.
Other Lesions
Premalignant changes arising in other oral lesions are uncommon. White lesions such as linea alba, leukoedema, and frictional keratosis are common in the oral cavity but have no propensity for malignant transformation. The health professional can usually identify them by patient history and clinical examination.
– See more at: https://www.oralcancerfoundation.org/
Hi, yes this post is genuinely pleasant and I have learned lot of things from it regarding blogging. thanks.
https://edutips.eu
Attractive section of content. I just stumbled upon your blog and in accession capital to assert that I acquire in fact enjoyed account your blog posts.
Anyway I’ll be subscribing to your augment and even I achievement you access consistently rapidly.
Good answer back in return of this difficulty with real arguments and telling everything on the topic of that.
This is a comment to the Premalignant lesion diagnosis in Dental Clinic – SkyDental admin. Your website is missing out on at least 300 visitors per day. Our traffic system will dramatically increase your traffic to your site: https://lis.ovh/is – We offer 500 free targeted visitors during our free trial period and we offer up to 30,000 targeted visitors per month. Hope this helps 🙂 Unsubscribe here: https://priscilarodrigues.com.br/url/11
I came to your Premalignant lesion diagnosis in Dental Clinic – SkyDental page and noticed you could have a lot more traffic. I have found that the key to running a website is making sure the visitors you are getting are interested in your subject matter. We can send you targeted traffic and we let you try it for free. Get over 1,000 targeted visitors per day to your website. Start your free trial: https://segundaibc.com.br/go/1i Unsubscribe here: https://priscilarodrigues.com.br/url/11
It’s difficult to decide on the great dental care service, however after reading through, this article it made me think a lot but I will
certainly try o use your advice down the road.
Good piece of content. Discovering more every day from this site.
These dentistry updates are really helpful to my family.
You know attempting to develop those good dental routines for my children.
Thanks for the information and facts. It’s difficult to
get a top quality and really valuable ideas. I will try to use those in the following appointment with
my dentist office.